Research by opioid manufacturers distorted authorship and overstated findings
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From 1999 to 2021, opioid overdoses caused over one million deaths in the US. The pharmaceutical industry has been held legally responsible in some cases for overstating the benefits and understating the risks of opioid use, leading to overprescribing that contributed to these deaths. Opioid manufacturers sponsor clinical trials to generate scientific evidence that supports use of their products to gain regulatory approval and to use in commercial materials to promote drug sales. Previous research has found industry-sponsored research may use dubious research practices to generate findings that justify use. Three examples of such research practices include inappropriate use of enriched enrollment trial design, ghost authorship, and overstatement of research findings.
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